Signed up for a brand new E3 Tennant and ready to build some pages, play with some pagelayouts..ect.
Found out that “acces was denied” even though I’m “Global” and “SharePoint Administrator”.
Guess what, SharePoint Online have now a new policy that by “default” disables custom scripting ect..
You can enable this by going to your SharePoint admin site | Settings and enable this, but you have to wait 24 hours.
or you can do this by PowerShell and you don’t need to wait 24 hours:
This will turn “On” the ability to deploy/customize pagelayouts ect… in Your SPO site.